Temodar |
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Temodar (temozolomide) is used to treat certain types of brain cancer. It is a chemotherapy drug that works by slowing cancer cell growth. In some patients, Temodar (temozolomide) decreases the size of brain tumors. Temodar is an oral alkylating agent for the treatment of newly diagnosed glioblastoma multiforme and refractory anaplastic astrocytoma.
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Temodar generic (generic - what is it?)
| Dosage |
Packing |
Price |
Add to basket |
| 100 mg |
15 caps |
USD 530.00 |
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| 250 mg |
15 caps |
USD 2150.00 |
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Temodar: Medications and Prescriptions
Generic name: temozolomide
Product Brand Name: Temodar
Temodar description
How Does It Work?
Temodar acts directly on the DNA in the cells in your body. DNA controls the growth of normal cells as well as brain tumor cells. Because these tumor cells grow much faster than normal cells, they are affected to a much greater extent by the effects of TEMODAR® Capsules.
Take Temodar (temozolomide) by mouth, usually once daily or as directed by your doctor. To reduce nausea and vomiting, take it on an empty stomach (1 hour before or 3 hours after a meal) or at bedtime, unless otherwise directed by your doctor. To make sure the amount of medicine in your body is kept at a constant level, take it at the same time every day in relation to a meal (e.g., always 1 hour before the evening meal or always 3 hours after the evening meal).
Swallow the capsules whole with a full glass of water (8 ounces or 240 milliliters). The dosage is based on your medical condition, body size, and response to therapy.
Do not crush, chew, or open the capsules. If the capsules are accidentally opened or damaged, avoid inhaling the medication, and do not let it touch the skin or mucous membranes (e.g., inside the nose). If contact occurs, flush the area with water. Since Temodar (temozolomide) 250mg can be absorbed through the skin, women who are pregnant or who may become pregnant should not handle Temodar (temozolomide) 250mg.
Do not increase your dose or take Temodar (temozolomide) more often without your doctor's approval. Your condition will not improve any faster and the risk of serious side effects may be increased.
Temodar Precautions
Before taking Temodar (temozolomide) tell your doctor or pharmacist if you are allergic to it; or to dacarbazine; or if you have any other allergies.
Before using Temodar (temozolomide) tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, decreased bone marrow function, blood cell disorders (e.g., anemia, leukopenia, thrombocytopenia).
Do not have immunizations/vaccinations without the consent of your doctor, and avoid contact with people who have recently received oral polio vaccine.
To lower the chance of getting cut, bruised or injured, use caution with sharp objects like safety razors or nail cutters, and avoid activities such as contact sports. Use a soft-bristle toothbrush to lower the risk of bleeding gums.
Wash your hands well to prevent the spread of infections.
The elderly may be more sensitive to the side effects of Temodar (temozolomide) especially the increased risk of infection and easy bruising/bleeding.
Women may be more sensitive to the side effects of Temodar (temozolomide) 250mg, especially the increased risk of infection and easy bruising/bleeding.
Temodar (temozolomide) is not recommended for use during pregnancy. It may harm an unborn baby. It is recommended that men and women use two effective forms of birth control (e.g., condoms and birth control pills) during treatment with Temodar (temozolomide) 250mg and for some time afterwards. Consult your doctor for more details and to discuss reliable forms of birth control.
It is not known if Temodar (temozolomide) 250mg passes into breast milk. Due to the potential risk to the infant, breast-feeding while using Temodar (temozolomide) is not recommended. Consult your doctor before breast-feeding.
Temodar misdose
For the best benefits, it is important to take each scheduled dose of Temodar (temozolomide) as directed. If you miss a dose of Temodar (temozolomide), contact your doctor to establish a new dosing schedule. Do not double the dose to catch up.
Temodar interaction
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.
Temodar (temozolomide) 250mg should not be used with the following medication because very serious interactions may occur: nalidixic acid.
If you are currently using the medication listed above, tell your doctor or pharmacist before starting Temodar (temozolomide) 250mg.
Before using Temodar (temozolomide) tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
Temodar Side Effects
Nausea, vomiting, loss of appetite, constipation, tiredness, weakness, and headache may occur. Nausea and vomiting can be quite severe. Drug therapy may be necessary to prevent or relieve nausea and vomiting. Not eating before your treatment may help relieve vomiting. Changes in diet and lifestyle, such as eating several small meals or limiting activity, may help lessen some of these effects. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
Temporary hair loss may occur. Normal hair growth should return after treatment has ended.
Remember that your doctor has prescribed Temodar (temozolomide) 250mg because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using Temodar (temozolomide) 250mg do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: mouth sores, swelling of the ankles/feet, easy bleeding or bruising, shortness of breath.
Temodar (temozolomide) can lower the body's ability to fight an infection. Notify your doctor promptly if you develop any signs of an infection such as: fever, chills, persistent sore throat, cough, burning/painful/frequent urination.
Although Temodar (temozolomide) is used to treat cancer, very rarely in some patients it may increase the risk of developing another form of cancer (of the bone marrow). Consult your doctor for more details. Tell your doctor immediately if you develop: swollen glands, unexplained or sudden weight loss, night sweats.
A very serious allergic reaction to Temodar (temozolomide) is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching, swelling, severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Temodar Storage
Store at room temperature at 77 degrees F (25 degrees C) away from light and moisture. Brief storage between 59-86 degrees F (15-30 degrees C) is permitted. Do not store in the bathroom. Keep all medicines away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.
See also: Brain cancer
Temodar notes:
Temodar (generic name temozolomide) interferes with the development of cancer cells and slows down the growth there by restricting their spread in the body. Temozolomide is an anti-cancer (antineoplastic or cytotoxic) chemotherapy drug. Along with radiation therapy, temozolomide is used to treat certain types of brain tumor in adults. It is sometimes given after other cancer medications.
Temodar side effects includes hives, difficulty in breathing, swelling of face/lips/tongue, seizure, numbness or tingling on one side of body, signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), loss of appetite, nausea and vomiting, unusual weakness, dry cough, weight loss, night sweats, pain or burning when urinating, white patches or sores inside mouth or on lips, hair loss, diarrhea, constipation mild skin rash, dizziness, blurred vision, insomnia, unusual or unpleasant taste in mouth.
The average unit price of Temodar prescription is estimated to be $500 (Temodar cost).
Although either surgery or radiation is the preferred treatment modality for patients with brain metastases from melanoma, temozolomide is the preferred chemotherapy if patients with brain metastases require systemic treatment. The addition of temozolomide to radiotherapy for newly diagnosed glioblastoma resulted in a clinically meaningful and statistically significant survival benefit with minimal additional toxicity.
Do not use this medication without telling doctor if you are pregnant. It could cause harm to the unborn baby. Use an effective form of birth control, and consult doctor if you become pregnant during treatment.
Store Temodar at room temperature away from moisture and heat.
Temodar notes:
Temozolomide is used for the treatment of brain cancer. An oral alkaline chemotherapy drug it helps slow down the growth of cancerous cells along with decreasing the size of the tumour. Temodar drugs like temozolomide along with radiation are used to treat glioblastoma multiforme or aggressive brain tumour which affects adults. It should be taken once a day or according to the doctor’s prescription and should be taken on empty stomach as it is known to cause vomiting and nausea.
Precautions:
Chewing the capsule or crushing of the capsule is not advisable. Avoid inhaling Temodar is harmful, pregnant women should not handle this drug. Medical history and allergies if any should be informed well in advance before the use of Temodar especially if suffering from blood disorders, kidney problems etc.
Avoid getting vaccinated or immunized, getting cut, using sharp instruments like razors, knives etc. Use tooth brush with soft bristles reduces the chances of bleeding gums etc. Pregnancy and breast feeding should be avoided when Temodar drug is used.
Temodar Side Effects: Side effects like loss of appetite, nausea, weakness, vomiting etc along with hair loss which is common in all types of cancers. Known to also reduce the resistance power in the body if you have persistent throat soreness, chills etc you need to consult your doctor.
Double dose should be avoided. Stopping the use of this drug without consulting your doctor is not recommended. Serious interactions are seen when using medications containing nalidixic acid ingredients.
Temodar cost is high but then there are certain websites offering Temodar at low cost. Temodar price also varies from place to place compare them with those websites selling them along with your neighborhood druggists. Though most insurance agencies, Medicare firms help cover up for the treatment, there are certain agencies that help in case you are not insured.
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Drug category:Anti-cancer drugs
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