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Orungal (Itraconazole) also known as Sporanox is a drug used in the treatment of fungal infections, such as aspergillosis, blastomycosis, histoplasmosis, and fungal infection localized to the toenails and fingernails (onychomycosis).
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| 100 mg |
15 tab ($3.93 per tab) |
USD 59.00 |
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| 100 mg |
28 tab ($3.82 per tab) |
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Orungal: Medications and Prescriptions
Generic name: Itraconazole
Product Brand Name: Orungal
Product Manufacturer: Janssen-Cilag
Orungal description
Orungal (Itraconazole) is a drug used in the treatment of fungal infections, such as aspergillosis, blastomycosis, histoplasmosis, and fungal infection localized to the toenails and fingernails (onychomycosis).
Prescribed for:
The treatment of fungal infections which are isolated to a small area of the body (localized) or throughout the body (systemic). It is active against fungal infections such as aspergillosis, blastomycosis, histoplasmosis, and fungal infection localized to the toenails and fingernails (onychomycosis).
Dosing:
Should be taken with a full meal. It is important to report any signs or symptoms that may suggest liver dysfunction so that the appropriate laboratory testing can be done. These signs include unusual fatigue, poor appetite, nausea and/or vomiting, yellowing of the eyes (jaundice), dark urine or pale stool.
Drug interactions:
Liver tests are monitored periodically in most patients, especially if receiving continuous treatment for more than one month. Itraconazole is used with caution in any patient with liver dysfunction.
The use of itraconazole in children is not recommended because it's safety has not been established.
Itraconazole is not used with following medications: terfenadine (Seldane), cisapride (Propulsid), astemizole (Hismanal), triazolam (Halcion) or midazolam (Versed).
Pregnancy:
There are no studies in pregnant women. Therefore, itraconazole is used for the treatment of systemic fungal infections in pregnancy only if it is felt that the benefit outweighs the potential risk. Itraconazole is not, however, used for the treatment of isolated onychomycosis (local fungal nail infections) in pregnant women or for those contemplating pregnancy.
Nursing mothers:
Itraconazole is excreted in human milk and therefore should not be administered to nursing women.
Side effects:
The most common side effects of itraconazole are minor and include nausea, vomiting, diarrhea, rash, edema, fatigue, dizziness. Less common but more serious side effects are liver enzyme elevation, hepatitis, and high blood pressure (hypertension).
Recommended dosage:
ADULTS:
Blastomycosis and Histoplasmosis
The usual dose is two 100-milligram capsules, taken after a full meal once a day. If you feel no improvement, or if there is evidence that the fungal disease has spread, your doctor will increase the dose 100 milligrams at a time to a maximum of 400 milligrams a day. Daily dosages above 200 milligrams a day should be divided into 2 smaller doses.
Aspergillosis
The usual dose is 200 to 400 milligrams a day. Treatment usually continues for a minimum of 3 months, until tests indicate that the fungal infection has subsided.
Onychomycosis
The usual dose for a toenail infection, whether or not fingernails are also involved, is 200 milligrams once a day for 12 weeks.
If only fingernails are infected, treatment is given in two 7-day-long sessions during which you take 200 milligrams of Sporanox twice a day, with a 3-week rest period between sessions.
Candidiasis, mouth and throat
The usual dose is 20 milliliters of oral solution a day for 1 to 2 weeks. If the infection does not go away, your dose will be changed to 10 milliliters twice a day.
Candidiasis, esophagus
The usual dose is 10 milliliters of oral solution a day for at least 3 weeks. You should continue the treatment for 2 weeks after your symptoms clear up. If necessary, the doctor may increase the dose to 20 milliliters a day.
Fungal infections in people with weakened immunity and fever
Recommended treatment starts with 200-milligram injections twice a day for 2 days followed by 200 milligrams injected once a day for up to 14 days. This may be followed by 20 milliliters of oral solution twice a day for up to a total of 28 days of treatment
CHILDREN:
The safety and effectiveness of Sporanox in children have not been established.
Preparations:
Capsule 100 mg.
Storage:
Itraconazole should be stored at room temperature in a tight container. Protect from light and moisture.
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Drug category:Antifungals
 Orungal
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