Lipitor |
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Atorvastatin was approved by the FDA in December of 1996.
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| Dosage |
Packing |
Price |
Add to basket |
| Atorvastatin 10 mg |
30 tab |
USD 39.00 |
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| Atorvastatin 20 mg |
30 tab |
USD 69.00 |
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| Atorvastatin 40 mg |
30 tab |
USD 81.00 |
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Lipitor generic (generic - what is it?)
| Dosage |
Packing |
Price |
Add to basket |
| 10 mg |
100 tab ($0.57 per tab, manuf. in India) |
USD 57.00 |
|
| 20 mg |
100 tab ($0.87 per tab, manuf. in India) |
USD 87.00 |
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Lipitor: Medications and Prescriptions
Generic name: Atorvastatin
Product Brand Name: Atorvastatin
Product Manufacturer: TEVA, KRKA, RG
Lipitor description
Drug class and mechanism:
Atorvastatin is an oral drug that lowers the level of cholesterol in the blood. It belongs to a class of drugs referred to as statins which includes lovastatin (Mevacor), simvastatin, (Zocor), fluvastatin (Lescol0, and pravastatin (Pravachol). All statins, including atorvastatin, prevent the production of cholesterol by the liver by blocking the enzyme that makes cholesterol, HMGCoA reductase. They lower total blood cholesterol as well as LDL cholesterol levels. (LDL cholesterol is believed to be the "bad" cholesterol that is primarily responsible for the development of coronary artery disease.) Lowering LDL cholesterol levels retards progression and may even reverse coronary artery disease. Unlike the other drugs in this class, atorvastatin also can reduce the concentration of triglycerides in the blood. High blood concentrations of triglycerides also have been associated with coronary artery disease. Atorvastatin was approved by the FDA in December of 1996.
Preparations:
Tablets of 10, 20, and 40 mg.
Storage:
Tablets should be stored below or at room temperature, 15-30°C (59-86°F).
Prescribed for:
Atorvastatin is used for the treatment of high cholesterol and triglyceride levels. High blood cholesterol is first treated with exercise, weight loss, and a diet low in cholesterol and saturated fats. When these measures fail to achieve enough cholesterol-lowering, medications such as atorvastatin may be added. The National Cholesterol Education Program (NCEP) has published treatment guidelines for use of these medications. These treatment guidelines take into account the level of LDL cholesterol as well as the presence of other factors that increase the risk for coronary artery disease such as diabetes, hypertension, cigarette smoking, low HDL cholesterol level, and family history of early coronary heart disease. The effectiveness of atorvastatin in lowering cholesterol is dose related, meaning that higher doses reduce cholesterol more. Blood cholesterol determinations are performed at regular intervals during treatment so that adjustments in doses can be made.
Dosing:
Atorvastatin is prescribed once daily. Starting doses are 10-40 mg. daily. It may be taken with or without food and at any time of day.
Drug interactions:
As with other drugs in this class, the risk of muscle breakdown (see "Side Effects," below) is increased when atorvastatin is given together with other medications such as cyclosporine (Sandimmune), gemfibrozil (Lopid), erythromycin and nicotinic acid.
Pregnancy:
It is not known if atorvastatin affects the fetus if taken during pregnancy. Atorvastatin may be used in pregnancy if the physician feels that its benefits outweigh the potential risks.
Nursing mothers:
It is not known if atorvastatin is secreted in breast milk. Therefore, the physician must decide whether to instruct a pregnant woman to continue taking atorvastatin and nursing if the benefits of treatment are judged to outweigh the potential risks, or to discontinue either nursing or atorvastatin if the potential risks are judged to outweigh the benefits.
Side effects:
Atorvastatin is generally well-tolerated, and side effects are rare. Minor side effects include constipation, diarrhea, fatigue, gas, heartburn, and headache. Atorvastatin should be used with caution in patients with alcohol or other liver diseases. Persistently abnormal liver tests during treatment are rare but may require discontinuation of the medication. Rare cases of muscle inflammation (myositis) and breakdown have been reported with other drugs in this class (HMGCoA reductase antagonists), and it is assumed that this side effect also may occur with atorvastatin. Muscle breakdown causes the release of muscle protein (myoglobin) into the blood and accumulation of the protein in the kidney tubules, resulting in kidney failure.
Caution! Before starting to take this medicine, it is vital that you should consult your doctor! Do not use it on your own initiative, without medical advice.
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Lipitor notes:
Lipitor generic Atorvastatin is a cholesterol lowering drug belonging to a class of drugs known as statins that includes lovastatin (Mevacor), simvastatin (Zocor), fluvastatin (Lescol), pravastatin (Pravachol) etc. Lipitor atorvastatin, also known as lipidor, lipator or liptor helps in preventing the production of cholesterol by the liver by obstructing the enzyme that produce cholesterol- the HMGCoA reductase. The drug atorvastatin is capable of reducing lower total blood cholesterol along with LDL cholesterol (bad cholesterol) levels. The lowering of LDL cholesterol prevents the development of coronary artery disease. It helps in reversing the disease and atorvastatin generic also helps in reducing the concentration of triglycerides in the blood that can also lead to coronary artery disease. It is approved by the FDA.
Treatment with atorvastatin is prescribed after the diet and exercise programs fail to lower cholesterol level in the blood. You can find treatment guidelines of this drug from the report published by the National Cholesterol Education Program (NCEP) have published regarding the use of these medications. Due to the reduction of bad cholesterol level and coronary artery disease, this drug in turn helps in reducing the risks for others diseases like diabetes, cigarette smoking, hypertension, low HDL cholesterol level along with family history of early coronary heart disease. The effectiveness of the drug depends on the lipitor dosage prescribed for lowering cholesterol. Thus, it means that higher the atorcvastaton mg dosage, higher would be the chance for cholesterol reduction. Lipitor hair loss conditions are also reported.
It is found to cause drug interactions with drugs like gemfibrozil (Lopid), cyclosporine (Sandimmune), erythromycin, nicotinic acid etc. Lipitor side effects include diarrhea, constipation, fatigue, heartburn, gas, and headache. lipitor and grapefruit should not be used together.
Weight loss news:
Adolescents weight control strategies identified – Says researchers
In a study published in Journal of the American Dietetic Association researchers have claimed to find the weight control strategy for adolescents, which is a major public health problem that impacts one out of every three children resulting in 4-5 million overweight youth in the United States. The researchers said that from the statistics available it is clearly seen that weight control strategies for adolescents is necessary.
130 adolescents were taken into participation for this study, out of them 62 were successful in losing weight and 68 were not. The adolescents were interrogated and from the data achieved, the authors evaluated weight control strategies, sedentary behaviors, dietary intake, physical activity, weighing frequency and current weight status. The participants were distributed in four different groups, the first was Healthy Weight Control Behaviors group which includes less calories food, more exercise, eating less high fat and junk food, drinking less soda, drinking more water and eating more fruits. The second category was Unhealthy Weight Control Behaviors which includes laxatives, vomiting, diuretics, smoking and fasting, the third category was Extreme Dietary Changes included use of liquid diet supplements, the Atkins diet, a structured diet, fasting and increased protein consumption and the fourth category Structured Behaviors included eating certain amount of calories, counting calories, recording food intake and working with a professional
The successful adolescents were reported from the first group. A higher percentage of adolescents who lost weight reported using 6 or more Healthy Weight Control Behaviors compared to those who did not lose weight. Less number of adolescents who lost weight reported using any of the Structured Behavior strategies assessed. Kerri Boutelle, PhD and co-author of this study stated that these findings provide a glimpse of optimism that adolescents can lose a significant amount of weight and maintain this weight loss and that there are no magical solutions but by eating more fruits and vegetables, eating less fat and decreasing sedentary time can help considerably to achieve the goal.
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Drug category:Antilipemic agents
 Lipitor
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