Jumex |
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Jumex (Selegiline), also known as Deprenyl, Eldepryl works by helping to conserve the amount of dopamine available by preventing the dopamine from being destroyed. While controversial, there is some evidence that this drug may slow the progression of Parkinson's disease, particularly early in the course of the disease.
keywords: jumex dosage, jumex tablets, jumex side effects, jumex mechanism, jumex package insert, jumex mg.
| Dosage |
Packing |
Price |
Add to basket |
| 5 mg |
50 tab ($0.78 per tab) |
USD 39.00 |
 |
| 5 mg |
150 tab ($0.71 per tab) |
USD 107.00 |
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| 5 mg |
300 tab ($0.65 per tab) |
USD 194.00 |
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| 10 mg |
30 tab ($1.53 per tab) |
USD 46.00 |
|
| 10 mg |
60 tab ($1.45 per tab) |
USD 87.00 |
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| 10 mg |
90 tab ($1.32 per tab) |
USD 119.00 |
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Jumex: Medications and Prescriptions
Generic name: Selegiline
Product Brand Name: Jumex
Product Manufacturer: Sanofi-Aventis
Jumex description
Description:
Jumex works by helping to conserve the amount of dopamine available by preventing the dopamine from being destroyed. While controversial, there is some evidence that this drug may slow the progression of Parkinson's disease, particularly early in the course of the disease. This drug is well-tolerated by most people, so many experts recommend using it despite the controversies.
Prescribed for:
Jumex is used to treat Parkinson's disease. Parkinson's disease is associated with low levels of a chemical called dopamine (doe PA meen) in your brain. The exact way that eldepryl works is unknown. However, it is believed that eldepryl prevents the breakdown of dopamine in your brain. Eldepryl is usually added to a treatment regimen after levodopa / carbidopa therapy begins to deteriorate.
Jumex is also used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease. It is also used to treat the same muscular conditions when they are caused by drugs such as chlorpromazine (Thorazine), fluphenazine (Prolixin), perphenazine (Trilafon), and others.
Drug Mechanism:
Jumex provides selective protection against the age-related degeneration of the dopaminergic nervous system. It protects sensitive dopamine-containing neurons from the age-associated increases in glial cells (non-neuron brain cells) and the monoamine oxidase (type B) that they contain. Jumex is the first selective inhibitor of MAO-B ever discovered, it is the only one used in clinical practice, and it remains the scientific reference standard for B-type inhibition after more than 40 years.
Jumex also competitively inhibits the uptake of dopamine, norepinephrine and epinephrine (collectively referred to as catecholamines) into neurons. This unique ability among the MAO inhibitors prevents the “cheese effect,” a dangerous hypertensive reaction caused by neural uptake of tyramine from tyramine-containing foods like aged cheeses, certain wines, yeast, beans, chicken liver and herring. Eldepryl exhibits no significant cheese effect at therapeutic dosages, and only minimal effects at extremely high dosages.
Jumex is a drug that was discovered around 1964-65. It was originally developed as a “psychic energizer,” designed to integrate some amphetamine-like brain effects with antidepressant effects. Also known as L-deprenyl, (-)-deprenyl, and selegiline, eldepryl has been intensively researched over the past 36 years - many hundreds of research papers on eldepryl have been published. Eldepryl has been shown to protect nerve cells against a wide (and growing) number of neurotoxins. Eldepryl has also been shown to be a “neuroprotection/ neurorescue agent” when nerve cells are exposed to damaging or stressful conditions.
Dosage Form:
The dose of Jumex will be different for different patients. Your doctor will determine the proper dose of eldepryl for you. Follow your doctor's orders or the directions on the label.
For the treatment of Parkinson's disease, the usual dose of eldepryl is 5 mg two times a day, taken with breakfast and lunch. Some patients may need less than this.
Drug Interactions:
Jumex can interact with other medications such as Demerol, and many depression medications. Be sure to talk to your doctor about any other medication you are taking before taking eldepryl. Although eldepryl is less likely than non-selective monoamine oxidase inhibitors to interact with tyramine in food, like other monoamine oxidase inhibitors it can produce life-threatening reactions when given with pethidine. Zornberg GL, et al. severe adverse interaction between pethidine and eldepryl.
Pregnancy:
Jumex has not been studied in pregnant women. However, this medicine has not been shown to cause birth defects or other problems in animal studies.
Nursing Mothers:
is not known whether eldepryl passes into the breast milk.
Dietary and Alcohol Considerations:
Alcoholic beverages or alcohol-free or reduced-alcohol beer and wine.
Foods that have a high tyramine content (most common in foods that are aged or fermented to increase their flavor), such as cheeses; fava or broad bean pods; yeast or meat extracts; smoked or pickled meat, poultry, or fish; fermented sausage (bologna, pepperoni, salami, summer sausage) or other fermented meat; sauerkraut; or any overripe fruit. If a list of these foods and beverages is not given to you, ask your health care professional to provide one.
Possible Side Effects:
Common side effects are nausea and vomiting. The most frequent side effects also include chest pain (severe); enlarged pupils; fast or slow heartbeat; headache (severe); increased sensitivity of eyes to light; increased sweating (possibly with fever or cold, clammy skin); nausea and vomiting (severe); stiff or sore neck.
Storage:
Keep this medication in the container it came in, tightly closed, and out of reach of children. Eldepryl should be stored at below 30°C (86°F) and away from excess heat and moisture (not in the bathroom). Heat or moisture may cause the medicine to break down. Keep away from light. Talk to your pharmacist about the proper disposal of your medication. Throw away any medication that is outdated or no longer needed. Be sure that any discarded medicine is out of the reach of children.
Package Size and Type:
Tablets: 5 mg, 10 mg.
Caution! Before starting to take this medicine, it is vital that you should consult your doctor! Do not use it on your own initiative, without medical advice. Also, you should read carefully important health information about this drug given here: www.nlm.nih.gov
keywords: jumex dosage, jumex tablets, jumex side effects, jumex mechanism, jumex package insert, jumex mg.
Jumex notes:
Jumex is also known by the names Selegiline, Deprenyl and Eldepryl. The drug helps to conserve the quantity of dopamine by keeping it from being destroyed. Even though this information is not confirmed but it is believed to slow the progress of Parkinson’s disease especially if it is provided in the early stages of the disease. Sanofi Aventis is the name of the manufacturer of Jumex. Most people can adapt to this drug so it is known to be safe for use. The exact way in which Jumex works is unknown but it is believed that it keeps the dopamine levels in your brain from breaking down. Jumex is also used to deal with stiffness, spasms, tremors and poor muscle control. As you grow older, the level of dopamine in your nervous system begins to degenerate. Jumex prevents from that degeneration taking place.
Jumex was discovered during 1964-65. Initially it was called a “psychic energizer” and made with the intention of providing some amphetamine like brain as well as anti depressant effects. The drug has been researched massively over the past 40 years and papers about how Jumex can keep nerve cells protected against a wide range of neurotoxins have also been published. The dosage of Jumex varies with different patients and you must consult a doctor before beginning your dose. In case of Parkinson’s disease, 5mg is the normal dose of eldepryl twice a day once at the time of breakfast and again during lunch. However some patients need a lesser dose.
Possible side effects of consuming Jumex are vomiting and nausea. Severe chest pain, changes in heart beat, enlarged pupils, increased perspiration, stiffness of neck and sore throat may also be experienced. In this case, a doctor must immediately be sent for. It is packaged in the form of tablets of 5mg and 10mg. The drug should be stored in the container you have purchased it in and not below 30 degrees Celsius, away from both heat and moisture. Do not consume Jumex is the expiry date has passed and it should be kept out of reach of children.
Parkinson's disease news:
Ghrelin found to increase resistance in parkinson's disease – A report.
The researchers at Yale School of Medicine have reported that ghrelin, a hormone produced in the stomach may be used to boost resistance or to slow down the development of parkinson's disease. Parkinson's disease is caused by a degeneration of dopamine neurons in an area of the midbrain known as the substantia nigra which is responsible for dopamine production.
Due to the reduced production of dopamine, parkinson's causes symptoms such as severe difficulty in walking, restricted movements, delays in moving, lack of appetite, difficulty eating, periods of remaining motionless as well as head and limb tremors. When such dopamine cells get sick and die, Parkinson's gets developed. Tamas Horvath chair and professor of comparative medicine and professor of neurobiology and obstetrics & gynecology at Yale School of Medicine said that ghrelin is protective of the dopamine neurons, in addition to its influence on appetite it is responsible for direct activation of the brain's dopamine cells. As this hormone originates from the stomach and it is circulating normally in the body so it could easily be used to boost resistance to Parkinson's.
The study was conducted on mice who received ghrelin supplementation and in mice that were deficient in ghrelin hormone and in the ghrelin receptor. When compared, mice with impaired ghrelin action in the brain had more loss of dopamine. Researchers said the results could be easily translated to human use because the ghrelin system is preserved through various species. In future studies will be conducted to determine ghrelin levels in both healthy individuals and parkinson's patients to determine whether altered ghrelin can be used as a biomarker of disease development and vulnerability.
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Drug category:Antiparkinson agents
 Jumex
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