Evista |
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EVISTA is the only medicine proven to reduce both the risk of spinal fractures due to osteoporosis and the risk of invasive breast cancer in postmenopausal women with osteoporosis. Estrogen is a hormone which among other actions, regulates the turnover (formation and destruction) of bone. Decreases in estrogen levels that are seen after menopause or after removal of the ovaries, lead to a loss of bone density and weakened bones, a condition called osteoporosis. Raloxifene decreases bone turnover and increases bone density although not to the same extent as estrogen itself. This makes bones stronger and prevents fractures in women with osteoporosis.
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28 tab ($3.54 per tab) |
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Evista generic (generic - what is it?)
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Evista: Medications and Prescriptions
Generic name: Raloxifene
Product Brand Name: Evista
Evista description
Why is this drug prescribed?
Evista is prescribed to treat and prevent osteoporosis, the brittle-bone disease that strikes some women after menopause. A variety of factors promote osteoporosis. The more factors that apply to you, the greater your chances of developing the disease. These factors include:
Caucasian or Asian descent
Slender build
Early menopause
Smoking
Drinking
A diet low in calcium
An inactive lifestyle
Osteoporosis in the family
Most important fact about this drug
Like estrogen, Evista reduces bone loss and increases bone density. However, Evista does not have estrogen-like effects on the uterus and breasts, and therefore is unlikely to increase the risk of cancer, as estrogen therapy sometimes can do. Although Evista has been shown to increase bone density over the course of a two-year study, its longer-term ability to prevent bone fractures has not yet been proven.
How should you take this medication?
Take Evista once daily, at any time, with or without food. Take calcium and vitamin D supplements as well, if you do not get enough in your diet. Avoid alcohol and tobacco. Do weight-bearing exercises to strengthen your bones.
--If you miss a dose... Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take a double dose.
--Storage instructions.. Store at room temperature.
What side effects may occur?
Evista has one very positive side effect: It lowers total cholesterol and LDL ("bad") cholesterol. It does not affect HDL ("good") cholesterol or triglyceride levels. The unwanted side effects of Evista cannot be predicted. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Evista.
· More common side effects may include:
Abdominal pain, arthritis, breast pain, bronchitis, chest pain, depression, diarrhea, dizziness, fever, flu symptoms, gas, gynecological problems, headache, hot flashes, increased cough, indigestion, infection, insomnia, joint pain, leg cramps, muscle ache, nasal inflammation, nausea, rash, sinusitis, sore throat, stomach and intestinal problems, sweating, swelling, tendon soreness, uterine discharge, urinary tract infection, vomiting, weight gain
Why should this drug not be prescribed?
Evista is not for use by women who are--or could become--pregnant. You should also avoid this drug if you have a history of blood clot formation, including deep vein thrombosis (blood clot in the legs), pulmonary embolism (blood clot in the lungs), and retinal vein thrombosis (blood clot in the retina of the eye), since Evista increases the risk of clots. Avoid the drug, too, if it gives you an allergic reaction.
Special warnings about this medication
Because of Evista's tendency to promote clots, you should not take it during long periods of immobilization such as recovery from surgery or prolonged bed rest, or for 72 hours beforehand. If you are scheduled for surgery, make sure the doctor is aware that you are taking Evista. For the same reason, if you are going on a trip where your movement will be restricted, make a point of periodically getting up and walking around. Evista is not needed prior to menopause and shouldn't be taken until menopause has passed. It has not been studied in premenopausal women and its use is not recommended. Use Evista with caution if you have congestive heart failure, a liver condition, or cancer. Be cautious, too, if you've had breast cancer in the past; the drug's effect in this situation is unknown.
If you develop unusual uterine bleeding or breast problems while taking Evista, tell your doctor immediately. Evista will not cure hot flashes. (In fact, it may cause them.) Nevertheless, never combine Evista with estrogen hormones. If you've had a problem with high blood triglyceride levels when taking estrogen, Evista may cause the same problem. However, it tends to lower cholesterol levels by 6 to 11 percent.
Possible food and drug interactions
If Evista is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Evista with the following:
Cholestyramine (Questran)
Clofibrate (Atromid-S)
Diazepam (Valium)
Diazoxide (Proglycem)
Ibuprofen (Advil, Motrin, Nuprin)
Indomethacin (Indocin)
Naproxen (Aleve, Anaprox, Naprosyn)
Warfarin (Coumadin)
Special information if you are pregnant or breastfeeding Evista can harm a developing baby. Do not use if you are or may become pregnant. Also avoid breastfeeding while taking Evista.
Recommended dosage
POSTMENOPAUSAL WOMEN
The recommended dosage is one 60-milligram tablet once a day.
Overdosage
There have not been any reports of overdose with Evista. However, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
Caution! Before starting to take this medicine, it is vital that you should consult your doctor! Do not use it on your own initiative, without medical advice.
key words: raloxifeno, raloxifen
Evista notes:
The generic name of Evista is raloxifeno and is prescribed for reducing the risk of spinal fractures that are caused due to osteoporosis. It is also commonly prescribed to reduce the risk for invasive breast cancer that is prone in postmenopausal women suffering from osteoporosis. The estrogen hormone that regulates the formation and destruction of bones in women usually decreases in levels after menopause in women or after the removal of the ovaries, as a result of which it leads to a loss of bone density and weakening of bones. This condition is known as osteoporosis. Evista is a powerful drug that is clinically proven in decreasing the bone turnover, which thereby helps in increasing the density of bone to some extend. Regular administration of raloxifeno by women with osteoporosis helps in making their bones stronger and thus controls the risks of fractures in women associated with osteoporosis.
Even though Evista can effectively help in strengthening the bones and control the loss of bone density in women after menopause as the Estrogen hormone does, still it cannot successfully offer estrogen-like effects on the breasts and uterus like the body hormone. Thus, estrogen therapies can unlikely paves way for cancer. In spite of the ability of this drug to increase the bone density in women, no strong evidence has been so far reported with the drug with the ability to prevent fractures of bone successfully after long-term usage. Use of alcohol and tobacco is strictly prohibited while using these drugs.
Some commonly found side effects of Evista include: bronchitis, abdominal, joint, chest and breast pain, arthritis, diarrhea, gynecological problems, nasal inflammation, urinary tract infection, intestinal problems, sinusitis, insomnia, depression, dizziness, flu symptoms, hot flashes, nausea, rash, infection, sweating, swelling, tendon soreness, uterine discharge, weight gain etc. It should not be used by pregnant women.
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Drug category:Bone resorption inhibitor
 Evista
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