Articles

p53 tumor suppressor, the "guardian of the genome"

Carcinogenesis is a process that consists of multiple stages, namely, the inactivation of the tumor suppressor gene, the activation of the oncogene, and complex interactions that occur between the tumor and the underlying host tissues. As a result of these stages put together, a highly aggressive metastatic phenotype develops.
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Calorie restriction and fasting helps to prevent cancer and tumours

Researchers at University Of Alabama at Birmingham have shown that calorie restricted diets specifically restriction in glucose can help human beings by increasing the life of cells. The finding is published online in FASEB journal which can lead to restriction of aging and prevention of cancer. Such type of calorie restriction can also lead to control of age related diseases. To carry out this study, researchers used human lung cells and precancerous human lung cells that were at the beginning of cancer development. The cells were grown under laboratory environment and were given normal or reduced level glucose.
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Degeneration in aging worms – A research

In the latest research on the soil nematode (roundworms which are most distinct phylum of pseudocoelomates ) C. Elegans , researchers at Wageningen University have found a new vision in the direction of their growth. With the increase in their age it has been found that genes become more chaotic and they also show declination in gene regulation. As the deteriorating process in humans and worms is same, the result of this study provides new intimation to the researchers for medication of geriatric diseases.
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